Heat oven to 375°F. Cook pasta per package until al dente; drain well and set aside.
Melt 3 tablespoons butter in large skillet over medium-high. Cook mushrooms 5-6 minutes until golden, onion another 3 minutes until softened, then garlic 30 seconds.
Sprinkle in flour; stir constantly 1 minute to remove raw taste.
Slowly whisk in broth and wine to prevent lumps; simmer 3-4 minutes until slightly thickened.
Reduce to medium-low; add cream, 1 cup Parmesan, thyme, salt, and pepper. Gently simmer 2-3 minutes until smooth and creamy.
Toss pasta and turkey in sauce to coat; transfer to greased 9x13-inch dish.
Mix mozzarella, remaining 1/2 cup Parmesan, and panko in small bowl; scatter evenly over. Dot with remaining 1 tablespoon butter.
Bake 25-30 minutes until golden and bubbling. Cool 5 minutes; garnish with parsley and serve hot.