Preheat oven to 375°F and line a baking sheet with parchment paper.
Unroll crescent dough on a lightly floured surface and press seams together to form a rectangle.
Spread pizza sauce evenly over the dough, leaving a half-inch border.
Layer mozzarella and pepperoni over the sauce, then sprinkle with Italian seasoning and garlic powder.
Roll tightly into a log from the long edge and cut into 1-inch rounds.
Place cut-side up on the baking sheet and brush tops with melted butter.
Bake 13-15 minutes until golden brown; serve with extra pizza sauce.