In a large mixing bowl, whisk together olive oil, lemon juice, garlic powder, onion powder, paprika, Italian seasoning, salt, and black pepper.
Add chicken tenderloins to the marinade and toss to coat evenly. Cover and refrigerate for at least 2 hours or up to 8 hours.
Preheat grill or grill pan to medium-high heat and lightly oil the grates.
Remove chicken from marinade and shake off excess. Grill tenders for 5-6 minutes per side until internal temperature reaches 165°F and juices run clear.
Let chicken rest for 5 minutes before serving.
Serve hot with your favorite dipping sauces or alongside Southern-style sides.