Halve jalapeños lengthwise; scoop seeds and membranes with spoon.

Mix cream cheese, cheddar, garlic powder, and onion powder in a medium bowl until combined.

Fill halves with cheese mixture, mounding slightly.

Wrap each with half a bacon slice; secure with toothpick.

Preheat air fryer to 370°F; arrange poppers in single layer with space between.

Cook 10-12 minutes until bacon is crispy and browned, flipping halfway if needed.

Cool 3-4 minutes before serving to avoid hot cheese burns.